297 research outputs found

    Carving out new business models in a small company through contextual ambidexterity: the case of a sustainable company

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    Business model innovation (BMI) and organizational ambidexterity have been pointed out as mechanisms for companies achieving sustainability. However, especially considering small and medium enterprises (SMEs), there is a lack of studies demonstrating how to combine these mechanisms. Tackling such a gap, this study seeks to understand how SMEs can ambidextrously manage BMI. Our aim is to provide a practical artifact, accessible to SMEs, to operationalize BMI through organizational ambidexterity. To this end, we conducted our study under the design science research to, first, build an artifact for operationalizing contextual ambidexterity for business model innovation. Then, we used an in-depth case study with a vegan fashion small e-commerce to evaluate the practical outcomes of the artifact. Our findings show that the company improves its business model while, at the same time, designs a new business model and monetizes it. Thus, our approach was able to take the first steps in the direction of operationalizing contextual ambidexterity for business model innovation in small and medium enterprises, democratizing the concept. We contribute to theory by connecting different literature strands and to practice by creating an artifact to assist managemen

    Medios publicitarios y su influencia en la captación de clientes del Minimarket Super, distrito de Casma año 2022

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    La presente tesis titulada ¨Medios publicitarios y su influencia en la captación de clientes del minimarket Super, distrito de Casma año 2022 ¨es un estudio de tipo cuali-cuantitativo y de alcance descriptivo, el cual permitió conocer los medios publicitarios más adecuados para obtener clientes. El universo de investigación fué de 32,284 personas y la muestra resultante se determinó en 194 personas, el análisis de datos se realizó con la estadística descriptiva, lo cual derivó en información para llegar al objetivo general: identificar los medios publicitarios adecuados para que un minimarket capte clientes en el distrito de Casma. Por los resultados obtenidos se puede considerar que las personas de 18 años a más en la provincia de Casma consideran las redes sociales, páginas web e internet, como medios publicitarios más influyentes, sin dejar de lado a los medios tradicionales como el periódico o la radio. Esto nos demuestra que la tecnología sumada a la pandemia, ha generado que cada vez más personas tengan acceso a un celular o computadora y pasen más tiempo en estos que antes. En la actualidad los potenciales clientes dan a conocer su preferencia por el constante uso de medios digitales que les permitan enterarse de productos y servicios de la manera más rápida y práctica posible, dejándose influir también por buenos precios y variedad de productos

    TERIA F. CHOPIN SOFRIDO DE FIBROSE CÍSTICA? REVISÃO HISTÓRICA

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    Introduction: the Pole Frédéric Chopin (1810-1849) suffered his entire live from pulmonary disease, diagnosed at the time as tuberculosis; cystic fibrosis is a likely diagnosis. Objetive and Methods: to describe Chopin’s illness as a case report. Five articles about his disease, in English,  were revised in the PubMed database. Results: since his childhood Chopin suffered from recurrent diarrhea, weight loss, dyspnea and respiratory infections. In 1838 he developed cough, fever and hemoptysis. The diagnosis was tuberculosis, even without changes in his thoracic auscultation; moreover, no acquaintance of Chopin contracted the disease. In the following years, he had productive cough, progressive dyspnea and cyanosis. In 1849 he had a three day bout of intense coughing and rest dyspnea, dying on the 17th of October. In his autopsy, cardiomegaly was the only visible alteration (possible cor pulmonale). His familiar history and infertility also suggest cystic fibrosis. Conclusion: Chopin’s disease was part of the tragedies that inspired him; although contemporary physicians had diagnosed tuberculosis, the medical knowledge of our days allows the development of other hypothesis, with cystic fibrosis being a strong contender.Introdução: o compositor polonês Fréderic Chopin (1810-1849) sofreu toda vida com uma afecção pulmonar, na época diagnoticada tuberculose; fibrose cística é um diagnóstico provável. Objetivo e Métodos: descrever a doença de Chopin como relato de caso. Revisados 5 artigos sobre sua doença, em inglês, na base de dados PubMed. Resultados: desde a infância Chopin sofreu de diarréia recorrente, perda de peso, dispnéia e infecções respiratórias. Em 1838 desenvolveu tosse, febre  e hemoptise. O diagnóstico foi tuberculose, nunca confirmado pela sua ausculta pulmonar; ainda, nenhum contato de Chopin adquiriu a doença. Nos próximos anos, teve tosse produtiva, dispnéia progressiva e cianose. Em 1849 sofreu três dias com tosse intensa e dispnéia ao repouso, falecendo em 17/10. À autópsia, cardiomegalia foi a única alteração descrita (possível cor pulmonale). Sua história familiar e esterilidade também sugerem fibrose cística. Conclusão: a doença de Chopin fez parte das tragédias que o inspiraram; embora os médicos da época tenham diagnosticado tuberculose, o conhecimento médico atual permite desenvolver outras hipóteses, sendo a fibrose cística extremamente plausível

    O impacto específico de toxinas urêmicas em domínios cognitivos : uma revisão

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    One of the mechanisms proposed for chronic kidney disease (CKD)-related cognitive impairment is the accumulation of uremic toxins due to the deterioration of the renal clearance function. Cognition can be categorized into five major domains according to its information processing functions: memory, attention, language, visual-spatial, and executive. We performed a review using the terms ‘uric acid’, ‘indoxyl sulfate’, ‘p-cresyl sulfate’, ‘homocysteine’, ‘interleukins’ and ‘parathyroid hormone’. These are the compounds that were found to be strongly associated with cognitive impairment in CKD in the literature. The 26 selected articles point towards an association between higher levels of uric acid, homocysteine, and interleukin 6 with lower cognitive performance in executive, attentional, and memory domains. We also reviewed the hemodialysis effects on cognition. Hemodialysis seems to contribute to an amelioration of CKD-related encephalopathic dysfunction, although this improvement occurs more in some cognitive domains than in others.Um dos mecanismos propostos para explicar o comprometimento cognitivo relacionado à doença renal crônica (DRC) é o acúmulo de toxinas urêmicas devido à deterioração da função de depuração renal. A cognição pode ser categorizada em cinco domínios principais de acordo com suas funções de processamento de informações: memória, atenção, linguagem, visual-espacial e executiva. Realizamos uma revisão usando os termos "ácido úrico", "indoxil sulfato", "p-cresil sulfato", "homocisteína", "interleucinas" e "paratormônio". Estes são os compostos que se mostraram fortemente associados ao comprometimento cognitivo na DRC na literatura. Os 26 artigos selecionados apontam para uma associação entre níveis mais elevados de ácido úrico, homocisteína e interleucina-6 com menor desempenho cognitivo nos domínios executivo, atenção e de memória. Também revisamos os efeitos da hemodiálise na cognição. A hemodiálise parece contribuir para uma melhoria da disfunção encefalopática relacionada à DRC, embora essa melhora ocorra mais em alguns domínios cognitivos do que em outros

    WHO ARE THE STUDENTS OF THE DENTISTRY PROGRAM AT ULBRA IN CANOAS, RS, WHAT THEY THINK AND WHAT THEY EXPECT OF THE JOB MARKET: A CROSS-SECTIONAL STUDY

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    Dentistry programs should prepare professionals with a generalist profile, having biological, scientific, technical, social and humanistic training. They should be trained for the reality of the job market and to practice Dentistry in both public and private settings, in order to provide leadership in the community in which they are placed. Objective: This study aims to analyze the socio-demographic profile, satisfaction with the program, self-evaluation of academic performance and expectations of the job market of students entering and exiting the Dentistry program of ULBRA/Canoas. Methodology: This is an observational, cross-sectional study conducted using a questionnaire with different questions for students entering and exiting the program in 2015. A questionnaire was developed with both open and closed objective, multiple-choice questions. It was given to 71 (86.5%) students enrolled in the program. Results: Most of the subjects are female, single, childless and between the ages of 17 and 36 years. Most chose Dentistry as a profession because they always liked or were interested in the health field. It was observed that the exiting students worked more in the areas of General Dentistry (90.4%) and Periodontics (77.0%) during their academic time, and intended to work in private practice (49.0%) and in the Unified Health System (65.0%). Conclusion: It was concluded that the profile of the entering and the exiting students is diverse, also that the students perceive that the greatest difficulty in the practice of Dentistry is the insertion and saturation of the job market

    Factores de riesgo materno fetales asociados a ruptura prematura de membranas en gestantes pretermino atendidas en el Hospital Nacional Hipólito Unanue durante el 2015

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    Objetivo: Determinar los factores de riesgo asociados a la ruptura prematura de membranas en gestantes pre término que han sido atendidas en el Hospital Nacional Hipólito Unanue durante el año 2015. Material y Métodos: Estudio observacional, retrospectivo, analítico, donde se incluyó al total de población pre término, siendo 261 gestantes, del cual se buscaron los datos de sus historias clínicas mediante una ficha de recolección, para luego ser tabulada en el programa Microsoft Excel y posteriormente el análisis estadístico se realizó con el programa SPSS v.20. Resultados: La prevalencia de ruptura prematura de membranas del total de gestantes pre término estudiadas correspondió al 45,2%. La edad materna tiene una asociación no significativa a la RPM con OR=1,176 (IC 95%: 0.716 a 1.933). Con respecto a la paridad, encontramos que el 61,9% son nulíparas y el 38,1% son multíparas; además tiene una asociación no significativa con la RPM OR=1,740 (IC 95%: 1.060 a 2.856). En los controles prenatales hubo 72% con menos de 6 controles prenatales y está asociado al RPM con OR=2,402 (IC 95%: 1.060 a 2.856). La gestación múltiple si está asociado a la RPM con OR=3,325 (IC 95%: 1.247 a 8.866), estando presente en un 12,7%. La infección del tracto urinario (ITU) estuvo presente en 33,1% de gestantes pre término con RPM, además está asociado a la RPM con OR=2,715 (IC 95%: 1.498 a 4.920). La infección cervico-vaginal estuvo presente en un 34,7%, además tiene asociación con la RPM OR=3,698 (IC 95%: 1.984 a 6.892). El antecedente de RPM, estuvo presente en 12,7%, además está asociado a la RPM con OR= 3,325 (IC 95%: 1.247 a 8.866). Por último, el polihidramnios se presentó en un 4,2%, teniendo asociación no significativa con la RPM OR=3,119 (IC 95%: 0.594 a 16.380). Conclusión: Los factores de riesgo maternos con más asociación y significancia estadística, en orden de mayor a menor, son: la infección cervico-vaginal, el antecedente de RPM, ITU, los CPN y por último la nuliparidad. De los factores de riesgo fetales, el embarazo múltiple mostró asociación con la RPM

    Projeto preliminar de estatorreator a parafina sólida com ancorador-injetor de chama integrados

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    Trabalho de Conclusão de Curso (graduação) — Universidade de Brasília, Faculdade de Tecnologia, Departamento de Engenharia Mecânica, 2020.Os sistemas de propulsão a jato denominados Ramjets têm sido objeto de estudo de diversos pesquisadores desde a sua primeira proposição em 1913, pelo francês René Lorin. Os Ramjets chamam bastante a atenção por conta de sua simplicidade mecânica, velocidades elevadas de voo (regime supersônico) e baixo custo, quando comparados a sistemas similares. Têm sido utilizados em aplicações militares, como exemplos, o míssil Brahmos e a peça de artilharia Nammo. No Brasil, é noticiado o desenvolvimento do míssil tático AV-TM 300, pelo Exército, que irá operar em regime subsônico, como um dos objetivos a serem alcançados pelo projeto estratégico Astros 2020. Contudo, é desconhecido que haja estudos no Brasil acerca do desenvolvimento de sistemas de propulsão supersônica. Com base nisso, a Universidade de Brasília se propõe a realizar o estudo sobre Ramjets a combustível sólido, utilizando a parafina como combustível, bem como, buscar alternativas para melhoria na eficiência desses sistemas, seja introduzindo novos elementos ou experimentando novas configurações. A parafina é escolhida por se mostrar um combustível bastante promissor, com elevada taxa de regressão e baixo custo operacional. Em suma, o trabalho terá como objetivo a busca por alternativas que proporcionem melhoria na eficiência dos sistemas Ramjets.Jet propulsion systems known as Ramjets have been the subject of study by many researchers since their first proposition in 1913 by the French René Lorin. Ramjets draw a lot of attention because of their mechanical simplicity, high flight speeds (supersonic regimes) and low cost when compared to similar systems. It has been used in military applications, such as the Brahmos missile and the Nammo artillery piece. In Brazil, the army’s development of the tactical missile AV-TM 300, which will operate in subsonic mode, is reported as one of the objectives to be achieved by the Astros 2020 strategic project. However, it is unknown that there are studies in Brazil on the development of supersonic propulsion systems. Based on this, the University of Brasilia proposes to conduct the study of solid fuel Ramjets, using paraffin as propellant, as well as, to search alternatives for improve efficiency of this systems experimenting new configurations. Paraffin is chosen because it is a very promising fuel, with high regression rate and low operating cost. The work will aim to find alternatives that improve the systems Ramjets efficiency

    ANÁLISE DO PROCESSO CRIATIVO EM QUADRINHOS POÉTICO-FILOSÓFICOS: ANTONIO AMARAL

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    Neste artigo apresentamos o artista piauense Antonio Amaral, que tem como destaque a produção de histórias em quadrinhos do gênero poético-filosófico – que são HQs necessariamente feitas para incitar o leitor a pensar, inovadoras e vanguardista em forma e conteúdo. Os pressupostos teóricos visam aproximar os processos criativos do autor com os descritos por artistas pesquisadores como Fayga Ostrower, Stephen Natchmanovitch, Rollo May e Cecília Salles. Os quadrinhos de Amaral se destacam, ainda, pela força poética e hermética de expressão, com influência do expressionismo e do abstracionismo aliado a textos um tanto quanto dadaístas

    Business model innovation influencing factors : an integrative literature review

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    Proposal to integrate the Business Model Innovation (BMI) influencing factors in a single framework. Twelve BMI influencing factors found through an integrative literature review. Factors grouped through an affinity diagram to design the framework architecture, containing four categories. The study highlights the importance for companies to consider the interrelationship between the influence factors to be successful in their BMI initiatives. This paper aims to provide an integrated framework that comprises influence factors for business model innovation, and describe them by exploring the linkages between different factors. An integrative literature review was conducted using PRISMA work flow to manage this kind of methodology. This work finds 12 main potential influence factors for business model innovation. All factors have been grouped into four different categories, using the affinity diagram approach. Business model innovation is a recent research topic, and not all its influence factors are agreed upon. Despite the importance of grouping, those already described in a single framework, there may be other relevant factors not mapped. Despite the existence of bibliographic material on specific influencing factors, there is, to the best of the authors’ knowledge, no study that integrates all the explored factors. This work contributes to literature by integrating the diverse factors into a single framework. It contributes to practice, enticing managers to reflect on their own environment, and on the possible paths to follow for succeeding with its business model innovations efforts15461061
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